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研究成果概要

研究室共出版学术著作27部,发表SCI收录论文400余篇,获授权发明专利200余项,授权国际专利21项;获得包括国家科技进步二等奖、国家技术发明二等奖、科技部重点领域创新团队、国家教学成果二等奖等多个国家和省部级奖项。与此同时,毕业研究生45-50人已成为大学和中科院研究所教授、研究员。


近3年代表性论文

[1] Zhen K., et al., Bio-Based Strategies for Producing Glycosaminoglycans and Their Oligosaccharides, Trends in Biotechnology, 2018. 36: 806-818. (IF2018= 13.578)

[2] Wu, Y., et al., CRISPRi allows optimal temporal control of N-acetylglucosamine bioproduction by a dynamic coordination of glucose and xylose metabolism in Bacillus subtilis Metabolic Engineering, Metabolic Engineering, 2018. 49:232-241. (IF2018= 7.674)

[3] Gu, Y., et al., Advances and prospects of Bacillus subtilis cellular factories: From rational design to industrial applications, Metabolic Engineering, 2018. 50:109-121. (IF2018= 7.674)

[4] Gu, Y., et al., Synthetic redesign of central carbon and redox metabolism for high yield production of N-acetylglucosamine in Bacillus subtilis, Metabolic Engineering, 2018. 51:59-69. (IF2018= 7.674)

[5] Lv. Y., et al., Engineering of an H2O2 Auto-Scavenging In Vivo Cascade for Pinoresinol Production, Biotechnology and Bioengineering, 2017. 114(9): 2066-2074. (IF2018= 3.952)

[6] Zhou. S., et al., Obtaining a Panel of Cascade Promoter-5'-UTR Complexes in Escherichia coli, ACS Synthetic Biology, 2017. 6(6)1065-1075. (IF2018= 5.316)

[7] Liu, Y., et al., A Metabolic engineering of Bacillus subtilis fueled by systems biology: recent advances and future directions, Biotechnology Advances, 2017. 35: 20-30. (IF2018= 11.452)

[8] Jin, P., et al., Production of specific-molecular-weight hyaluronan by metabolically engineered Bacillus subtilis, Metabolic Engineering, 2016,35: 21-30. (IF2018= 7.674)

[9] Jin, P., et al., Combinatorial evolution of enzymes and synthetic pathways using one-step PCR, ACS Synthetic Biology, 2016, 5: 259-268. (IF2018= 5.316)



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