食品合成生物学与生物制造团队

185. Zhou JW, Liu LM, Shi ZP, Du GC, *Chen J. ATP in current biotechnology: Regulation, applications and perspectives. Biotechnology Advances, 2009. 27(1): 94-101.

184. Zhou JW, Huang LX, Liu LM, *Chen J. Enhancement of pyruvate productivity by inducible expression of a F0F1-ATPase inhibitor INH1 in Torulopsis glabrata CCTCC M202019. Journal of Biotechnology, 2009. 144(2): 120-126.

183. Zhou JW, Dong ZY, Liu LM, Du GC, *Chen J. A reusable method for construction of non-marker large fragment deletion yeast auxotroph strains: A practice in Torulopsis glabrata. Journal of Microbiological Methods, 2009. 76(1): 70-74.

182. Zhang DX, Zhu Y, *Chen J. Microbial transglutaminase production: Understanding the mechanism. Biotechnology and Genetic Engineering Reviews, 2009. 26: 205-222.

181. Zhang DD, Liang N, Shi ZP, Liu LM, *Chen J, Du GC. Enhancement of α-ketoglutarate production in Torulopsis glabrata: Redistribution of carbon flux from pyruvate to α-ketoglutarate. Biotechnology and Bioprocess Engineering, 2009. 14(2): 134-139.

180. Yan HJ, Hua ZZ, Qian GS, Wang M, Du GC, *Chen J. Effect of cutinase on the degradation of cotton seed coat in bio-scouring. Biotechnology and Bioprocess Engineering, 2009. 14(3): 354-360.

179. Yan HJ, Hua ZZ, Qian GS, Wang M, Du GC, *Chen J. Analysis of the chemical composition of cotton seed coat by Fourier-transform infrared (FT-IR) microspectroscopy. Cellulose, 2009. 16(6): 1099-1107.

178. Yan GL, *Chen J, Hua ZZ. Roles of H2O2 and OH center dot radical in bactericidal action of immobilized TiO2 thin-film reactor: An ESR study. Journal of Photochemistry and Photobiology a-Chemistry, 2009. 207(2-3): 153-159.

177. Xu KW, Liu H, Du GC, *Chen J. Real-time PCR assays targeting formyltetrahydrofolate synthetase gene to enumerate acetogens in natural and engineered environments. Anaerobe, 2009. 15(5): 204-213.

176. West NP, Chow FME, Randall EJ, Wu J, *Chen J, Ribeiro JMC, Britton WJ. Cutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identification. FASEB Journal, 2009. 23(6): 1694-1704.

175. Wang Y, Wang ZH, Xu QL, Du GC, Hua ZZ, Liu LM, Li JH, *Chen J. Lowering induction temperature for enhanced production of polygalacturonate lyase in recombinant Pichia pastoris. Process Biochemistry, 2009. 44(9): 949-954.

174. Wang Y, Wang ZH, Du GC, Hua ZZ, Liu LM, Li JH, *Chen J. Enhancement of alkaline polygalacturonate lyase production in recombinant Pichia pastoris according to the ratio of methanol to cell concentration. Bioresource Technology, 2009. 100(3): 1343-1349.

173. Wang Q, Fan XR, Cui L, Wang P, Wu J, Chen J. Plasma-Aided Cotton Bioscouring: Dielectric Barrier Discharge Versus Low-Pressure Oxygen Plasma. Plasma Chemistry and Plasma Processing, 2009. 29(5): 399-409.

172. Nie YQ, Liu H, Du GC, *Chen J. Acetate production by a coupled syntrophic acetogenesis with homoacetogenesis process: Effect of sludge inoculum concentration. Environmental Technology, 2009. 30(2): 141-150.

171. Liu ZY, Zhang DX, Hua ZZ, Li JH, Du GC, *Chen J. A newly isolated Paecilomyces sp WSH-L07 for laccase production: isolation, identification, and production enhancement by complex inducement. Journal of Industrial Microbiology & Biotechnology, 2009. 36(10): 1315-1321.

170. Liu XL, Liu H, Du GC, *Chen J. Improved bioconversion of volatile fatty acids from waste activated sludge by pretreatment. Water Environ Res, 2009. 81(1): 13-20.

169. Liu L, Yang HQ, Zhang DX, Du GC, *Chen J, Wang M, Sun J. Enhancement of hyaluronic acid production by batch culture of Streptococcus zooepidemicus via the addition of n-dodecane as an oxygen vector. Journal of Microbiology and Biotechnology, 2009. 19(6): 596-603.

168. Liu L, Yang HQ, Du GC, *Chen J, Wang M. Enhanced hyaluronic acid production of Streptococcus zooepidemicus by shifting dissolved oxygen level based on broth rheology and oxygen mass transfer characteristics. Food Biotechnology, 2009. 23(2): 148-161.

167. Liu L, Sun J, Zhang DX, Du GC, *Chen J, Xu WB. Culture conditions optimization of hyaluronic acid production by Streptococcus zooepidemicus based on radial basis function neural network and quantum-behaved particle swarm optimization algorithm. Enzyme and Microbial Technology, 2009. 44(1): 24-32.

166. Liu L, Sun J, Xu WB, Du GC, *Chen J. Modeling and optimization of microbial hyaluronic acid production by Streptococcus zooepidemicus using radial basis function neural network coupling quantum-behaved particle swarm optimization algorithm. Biotechnology Progress, 2009. 25(6): 1819-1825.

165. Liu L, Du GC, *Chen J, Zhu Y, Wang M, Sun J. Microbial production of low molecular weight hyaluronic acid by adding hydrogen peroxide and ascorbate in batch culture of Streptococcus zooepidemicus. Bioresource Technology, 2009. 100(1): 362-367.

164. Liu L, Du GC, *Chen J, Wang M, Sun J. Comparative study on the influence of dissolved oxygen control approaches on the microbial hyaluronic acid production of Streptococcus zooepidemicus. Bioprocess and Biosystems Engineering, 2009. 32(6): 755-763.

163. Liu H, Li GW, Zhang M, Du GC, Chen J. Real-time PCR quantification of ammonia-oxidising bacteria in aerobic granular sludge and activated sludge influenced by pentachlorophenol. International Journal of Environment and Pollution, 2009. 37(2-3): 256-265.

162. Lin J, Liao XY, Zhang J, Du GC, *Chen J. Enhancement of glutathione production with a tripeptidase-deficient recombinant Escherichia coli. J. Ind. Microbiol. Biotechnol., 2009. 36(12): 1447-1452.

161. Lin J, Liao XY, Du GC, *Chen J. Enhancement of glutathione production in a coupled system of adenosine deaminase-deficient recombinant Escherichia coli and Saccharomyces cerevisiae. Enzyme Microb. Technol., 2009. 44(5): 269-273.

160. Liang GB, Liao XY, Du GC, *Chen J. A new strategy to enhance glutathione production by multiple H2O2-induced oxidative stresses in Candida utilis. Bioresource Technology, 2009. 100(1): 350-355.

159. Liang GB, Du GC, *Chen J. Salt-induced osmotic stress for glutathione overproduction in Candida utilis. Enzyme and Microbial Technology, 2009. 45(4): 324-329.

158. Li ZF, Zhang JY, Wang M, Gu ZB, Du GC, Li JK, Wu J, *Chen J. Mutations at subsite-3 in cyclodextrin glycosyltransferase from Paenibacillus macerans enhancing alpha-cyclodextrin specificity. Applied Microbiology and Biotechnology, 2009. 83(3): 483-490.

157. Li ZF, Zhang JY, Sun Q, Wang M, Gu ZB, Du GC, Wu J, *Chen J. Mutations of lysine 47 in cyclodextrin glycosyltransferase from Paenibacillus macerans enhance beta-cyclodextrin specificity. Journal of Agricultural and Food Chemistry, 2009. 57(18): 8386-8391.

156. Li ZF, Li B, Liu ZG, Wang M, Gu ZB, Du GC, Wu J, *Chen J. Calcium leads to further increase in glycine-enhanced extracellular secretion of recombinant a-cyclodextrin glycosyltransferase in Escherichia coli. J. Agr. Food Chem., 2009. 57(14): 6231-6237.

155. He GQ, Huo GH, Liu LM, Zhu Y, Du GC, *Chen J. Enhanced cutinase production of Thermobifida fusca by a two-stage batch and fed-batch cultivation strategy. Biotechnology and Bioprocess Engineering, 2009. 14(1): 46-51.

154. Gong RM, Guo PZ, Chen J, Huang FH. Removing Bisphenol A from Aqueous Solution by Phosphorylated Cotton in the Presence of Cetyl Trimethyl Ammonium Bromide. Environmental Engineering Science, 2009. 26(10): 1561-1566.

153. Gong R, Liang J, Chen J, Huang F. Removal of bisphenol A from aqueous solution by hydrophobic sorption of hemimicelles. International Journal of Environmental Science and Technology, 2009. 6(4): 539-544.

152. Feng L, Li XF, Du GC, *Chen J. Characterization and fouling properties of exopolysaccharide produced by Klebsiella oxytoca. Bioresource Technology, 2009. 100(13): 3387-3394.

151. Feng L, Li XF, Du GC, *Chen J. Adsorption and fouling characterization of Klebsiella oxytoca to microfiltration membranes. Process Biochemistry, 2009. 44(11): 1289-1292.

150. Zhuge B, Du GC, Shen W, Zhuge J, *Chen J. Expression of a Bacillus subtilis pectate lyase gene in Pichia pastoris. Biochemical Engineering Journal, 2008. 40(1): 92-98.

149. Zhao HF, Fan W, Dong JJ, Lu J, *Chen J, Shan LJ, Lin Y, Kong WB. Evaluation of antioxidant activities and total phenolic contents of typical malting barley varieties. Food Chemistry, 2008. 107(1): 296-304.

148. Zhang Y, Du GC, Fan XR, *Chen J. Effects and statistical optimization of fermentation conditions on growth and poly (vinyl alcohol)-degrading enzyme production of Streptomyces venezuelae GY1. Biocatalysis and Biotransformation, 2008. 26(5): 430-436.

147. Zhang DX, Wang M, Du GC, Zhao QX, Wu J, *Chen J. Surfactant protein of the Streptomyces subtilisin inhibitor family inhibits transglutaminase activation in Streptomyces hygroscopicus. Journal of Agricultural and Food Chemistry, 2008. 56(9): 3403-3408.

146. Zhang D, Wang M, Wu J, Cui L, Du G, *Chen J. Two different proteases from Streptomyces hygroscopicus are involved in transglutaminase activation. Journal of Agricultural and Food Chemistry, 2008. 56(21): 10261-4.

145. Wei GY, Wang DH, *Chen J. Overproduction of glutathione by L-cysteine addition and a temperature-shift strategy. Biotechnology and Bioprocess Engineering, 2008. 13(3): 347-353.

144. Wang Q, Fan X, Yuan J, Wang P, Cui L, Chen J. Optimization of two-step cotton scouring with beta-cyclodextrin and alkaline pectinase. Engineering in Life Sciences, 2008. 8(3): 339-343.

143. Somasiri W, Li XF, Ruan WQ, *Chen J. Evaluation of the efficacy of upflow anaerobic sludge blanket reactor in removal of colour and reduction of COD in real textile wastewater. Bioresource Technology, 2008. 99(9): 3692-3699.

142. Shi JL, Li Y, Zheng Y, Zhu Y, Zhang XP, Du GC, *Chen J. Tryptophan supplementation and pH adjustment for optimizing the sporulation of Coniothyrium minitans. Biotechnology Letters, 2008. 30(2): 259-262.

141. Nie YQ, Liu H, Du GC, *Chen J. Acetate yield increased by gas circulation and fed-batch fermentation in a novel syntrophic acetogenesis and homoacetogenesis coupling system. Bioresource Technology, 2008. 99(8): 2989-2995.

140. Lu X, Hua ZZ, Du GC, Ma XL, Ca JH, Yang ZP, *Chen J. Scavenging of free radicals in gas-phase mainstream cigarette smoke by immobilized catalase at filter level. Free Radical Research, 2008. 42(3): 244-252.

139. Long L, Du GC, *Chen J, Miao W, Jun S. Influence of culture modes on the microbial production of hyaluronic acid by Streptococcus zooepidemicus. Biotechnology and Bioprocess Engineering, 2008. 13(3): 269-273.

138. Liu XL, Liu H, Chen YY, Dul GC, Chen J. Effects of organic matter and initial carbon-nitrogen ratio on the bioconversion of volatile fatty acids from sewage sludge. Journal of Chemical Technology and Biotechnology, 2008. 83(7): 1049-1055.

137. Liu XL, Liu H, Chen YY, Du GC, *Chen J. Effects of organic matter and initial carbon–nitrogen ratio on the bioconversion of volatile fatty acids from sewage sludge. Journal of Chemical Technology & Biotechnology, 2008. 83(7): 1049-1055.

136. Liu XL, Liu H, Chen JH, Du GC, *Chen J. Enhancement of solubilization and acidification of waste activated sludge by pretreatment. Waste Management, 2008. 28(12): 2614-2622.

135. Liu X, Liu H, Chen Y, Du G, Chen J. Effects of organic matter and initial carbon–nitrogen ratio on the bioconversion of volatile fatty acids from sewage sludge. Journal of Chemical Technology & Biotechnology, 2008. 83(7): 1049-1055.

134. Liu L, Wang M, Du G, *Chen J. Enhanced hyaluronic acid production of Streptococcus zooepidemicus by an intermittent alkaline-stress strategy. Letters in Applied Microbiology, 2008. 46(3): 383-388.

133. Liu L, Du GC, *Chen J, Wang M, Sun J. Influence of hyaluronidase addition on the production of hyaluronic acid by batch culture of Streptococcus zooepidemicus. Food Chemistry, 2008. 110(4): 923-926.

132. Liu L, Du G, *Chen J, Wang M, Sun J. Enhanced hyaluronic acid production by a two-stage culture strategy based on the modeling of batch and fed-batch cultivation of Streptococcus zooepidemicus. Bioresource Technology, 2008. 99(17): 8532-8536.

131. Liu J, Li Q, Dong J, *Chen J, Go G. Multivariate modeling of aging in bottled lager beer by principal component analysis and multiple regression methods. Journal of Agricultural and Food Chemistry, 2008. 56(16): 7106-7112.

130. Liu J, Dong JJ, Li Q, *Chen J, Gu GX. Investigation of new indexes to evaluate aging of bottled lager beer. Journal of the American Society of Brewing Chemists, 2008. 66(3): 167-173.

129. Liu H, Li GW, Li XF, *Chen J. Molecular characterization of bacterial community in aerobic granular sludge stressed by pentachlorophenol. Journal of Environmental Sciences-China, 2008. 20(10): 1243-1249.

128. Liao XY, Deng TN, Zhu Y, Du GC, *Chen J. Enhancement of glutathione production by altering adenosine metabolism of Escherichia coli in a coupled ATP regeneration system with Saccharomyces cerevisiae. J. Appl. Microbiol., 2008. 104(2): 345-352.

127. Liang GB, Liao XY, Du GC, *Chen J. Optimization of amino acids addition for efficient production of glutathione in Candida utilis. Biochemical Engineering Journal, 2008. 41(3): 234-240.

126. Liang GB, Du GC, *Chen J. Enhanced glutathione production by using low-pH stress coupled with cysteine addition in the treatment of high cell density culture of Candida utilis. Letters in Applied Microbiology, 2008. 46(5): 507-512.

125. Liang GB, Du GC, *Chen J. A novel strategy of enhanced glutathione production in high cell density cultivation of Candida utilis - Cysteine addition combined with dissolved oxygen controlling. Enzyme and Microbial Technology, 2008. 42(3): 284-289.

124. Liang G, Liao X, Du G, *Chen J. Elevated glutathione production by adding precursor amino acids coupled with ATP in high cell density cultivation of Candida utilis. Journal of Applied Microbiology, 2008. 105(5): 1432-1440.

123. Li XF, Li YJ, Liu H, Hua ZZ, Du GC, *Chen J. Correlation between extracellular polymeric substances and aerobic biogranulation in membrane bioreactor. Separation and Purification Technology, 2008. 59(1): 26-33.

122. Hu QH, Li XF, Liu H, Du GC, *Chen J. Enhancement of methane fermentation in the presence of Ni2+ chelators. Biochemical Engineering Journal, 2008. 38(1): 98-104.

121. Hu QH, Li XF, Du GC, Chen J. Effect of nitrilotri acetic acid on bioavailability of nickel during methane fermentation. Chemical Engineering Journal, 2008. 143(1-3): 111-116.

120. Hu QH, Li XF, Du GC, *Chen J. Effect of nitrilotriacetic acid on bioavailability of nickel during methane fermentation. Chemical Engineering Journal, 2008. 143(1-3): 111-116.

119. Hu QH, Li XF, *Chen J. Effect of nitrilotriacetic acid on batch methane fermentation of sulfate-containing wastewater. Process Biochemistry, 2008. 43(5): 553-558.

118. Hao JG, Dong JJ, Speers RA, Shen W, Shan LJ, Fan W, Li Q, Gu GX, Chen J. Construction of a Single PEP4 Allele Deletion in Saccharomyces carlsbergensis and a Preliminary Evaluation of Its Brewing Performance. Journal of the Institute of Brewing, 2008. 114(4): 322-328.

117. Gonga RM, Zhong KD, Hu Y, Chen J, Zhu GP. Thermochemical esterifying citric acid onto lignocellulose for enhancing methylene blue sorption capacity of rice straw. Journal of Environmental Management, 2008. 88(4): 875-880.

116. Gong RM, Zhu SX, Zhang DM, Chen J, Ni SJ, Guan R. Adsorption behavior of cationic dyes on citric acid esterifying wheat straw: kinetic and thermodynamic profile. Desalination, 2008. 230(1-3): 220-228.

115. Cui L, Du GC, Zhang DX, Fan XR, *Chen J. Stability and conformational changes of transglutaminase from Streptomyces hygroscopicus in ethanol-aqueous medium. Process Biochemistry, 2008. 43(8): 887-891.

114. Cui L, Du GC, Zhang DX, *Chen J. Thermal stability and conformational changes of transglutaminase from a newly isolated Streptomyces hygroscopicus. Bioresource Technology, 2008. 99(9): 3794-3800.

113. Cui L, Du GC, *Chen J, Wang Q, Wang P, Fan XR. Effect of microbial transglutaminase on dyeing properties of natural dyes on wool fabric. Biocatalysis and Biotransformation, 2008. 26(5): 399-404.

112. Chen S, Tong X, Woodard RW, Du GC, Wu J, *Chen J. Identification and characterization of bacterial cutinase. Journal of Biological Chemistry, 2008. 283(38): 25854-25862.